Fibromyalgia is something of a mystery. It can’t be detected with scans or blood tests, yet it causes lifelong pain for millions of people. The disease mainly affects women (about 75-90% of cases), causing pain all over the body. Because not all healthcare professionals are adept at identifying and diagnosing fibromyalgia, reported rates of the…
Women with Cushing’s syndrome may be misdiagnosed with fibromyalgia — a chronic condition characterized by widespread pain and mental distress — despite showing Cushing’s symptoms, a new case series report demonstrates. The researchers say these misdiagnoses of fibromyalgia, occurring in a trio of Cushing’s syndrome patients across three countries, highlight the difficulties of diagnosing women who experience…
Fibromyalgia is remarkably more common in women than it is in men, but when it comes to feeling its effects, there is little difference between the sexes, according to results of a new study published in the journal Pain Research and Management. Fibromyalgia is a poorly understood disorder characterized by deep tissue pain, fatigue, depression…
Key Takeaways TNX-102 SL significantly improved pain, sleep, fatigue, and functioning in fibromyalgia patients, meeting primary and secondary endpoints in a phase 3 trial. The FDA approved TNX-102 SL in 2025, marking the first new fibromyalgia treatment in over 15 years and the fourth overall. Investigators evaluated whether targeting sleep-related neurophysiology with bedtime TNX-102 SL…
The US Food and Drug Administration (FDA) has approved cyclobenzaprine hydrochloride sublingual tablets (Tonmya; Tonix Pharmaceuticals) for the treatment of fibromyalgia in adults, marking the first new therapy for the condition in more than 15 years, according to a company news release. “The FDA approval of Tonmya as a first-line treatment for fibromyalgia represents a…
In 2001, Emily Shaules was an active, happy 25-year-old lawyer living in Chicago when a casual toss of her hair triggered a sudden, excruciating snap in her neck. Fearing she might have torn something or given herself whiplash, she headed to the emergency room, where she was diagnosed with a pulled muscle, prescribed Vicodin, and…
In the absence of a blood test, clinicians rely on patient-reported symptoms and a physical evaluation of pain to diagnose fibromyalgia. Researchers from Ohio State University have identified a “metabolic fingerprint” of the disease that increases the probability a reliable blood test may be designed. The investigators analyzed blood samples from 121 participants with similar…
Fibromyalgia appears to occur at higher rates among patients with Behçet’s disease than in the general population. What are the implications? A number of studies have explored the prevalence of fibromyalgia in people with Behçet’s disease as well as the potential impact of fibromyalgia on Behçet’s disease activity. Behçet’s disease is a chronic inflammatory condition…
WHEN she was just 13, Bethan Bourne began showing fibromyalgia symptoms. Now 32, and having lived with the condition since her early teens, the Wokingham resident has commented on a new landmark study that has for the first time identified the genetic risk factors of fibromyalgia. Led by King’s College London, the research analysed data…
Lady Gaga Is Irritated By People Who Don’t Believe Her Fibromyalgia Pain Is Real Lady Gaga’s experience highlights a painful reality for many people living with invisible illnesses: being sick doesn’t always mean looking sick. When others cannot see the pain, fatigue, or neurological symptoms someone is experiencing, it can be easy for them to…