Fibromyalgia and Coexisting Chronic Pain Syndromes
Fibromyalgia is associated with many somatic symptoms, including fatigue, gastrointestinal complaints, and headaches. Five physical and psychological symptoms, called the SPADE pentad—sleep disturbance, pain, anxiety, depression, and low energy/fatigue—have been especially prominent in subjects with other chronic pain conditions, making the differential diagnosis sometimes difficult. Indeed, there is a significant overlap between fibromyalgia and what…